A significant portion of COVID-19 patients develop pneumonia and acute respiratory distress syndrome (ARDS), necessitating ventilator support. ... Cody Cleveland & Giovanni Traverso. 5, 533–536 (1988). A robotic culture system for the high-throughput analysis of drug transport in porcine gastrointestinal tissue explants accurately predicts the absorption of orally taken drugs in the human gut. Science 354, 6316 (2016), 1109--1109. Here we describe a method that can quantify such variation at a scale and ease heretofore unattainable. Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins. Minding the billions: Ultra-wideband localization for deployed rfid tags. Quantifying the value of orally delivered biologic therapies: a … The Plant Journal 84 (4), 718-732. , 2015. Google Scholar; Yunfei Ma, Nicholas Seby, and Fadel Adib. The development of novel drug-device combinations will require careful consideration of the pharmacokinetics of this delivery route and moreover require significant formulation development to maintain the appropriate dose and activity of the API. 2015. Ming Li, Ameya R. Kirtane, Juri Kiyokawa, Hiroaki Nagashima, Aaron Lopes, Zain A. Tirmizi, Christine K. Lee, Giovanni Traverso, Daniel P. Cahill and Hiroaki Wakimoto Ming Li Find this author on Google Scholar Google Scholar Digital Library; Kiwan Maeng, Alexei Colin, and Brandon Lucia. Search articles by 'Giovanni Traverso'. 1 Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139 ( USA) 5 Biomedical Engineering Program, Faculty of Engineering, Chulalongkorn University, Bangkok, 10330 ( THA) Find this author on Google Scholar. The iMASC system was designed as a reusable liquid silicone rubber mask … Article Google Scholar 2. Levonorgestrel was detected in the serum of pigs for 1 month after oral administration of a single dose. Reducing the frequency at which a patient must take a medication can improve patient adherence. Advisors: Prof. Robert Langer and Prof. Giovanni Traverso Research Interests: Ingestible and implantable biomedical devices Hobbies: Biking, Baking, Playing Foosball Email: agabram at stanford.edu Google Scholar… Novel technologies is part of five focus areas of the Challenges in IBD Research document, which also includes preclinical human IBD mechanisms, 1 environmental triggers, 2 precision medicine 3 and pragmatic clinical research. Diverse genetic subtypes of malignant glioma are sensitive to selective inhibition of the NAD+ salvage pathway enzyme nicotinamide phosphoribosyltransferase (NAMPT). E-mail: ctraverso@partners.org. The ability for systemic delivery of insulin was evaluated through serial injections via the gastric, duodenal, and colonic mucosa of approximately 75–80 kg Yorkshire pigs.Subcutaneous insulin administration was used as a comparator (Fig. of Mechanical Engineering, MIT; Brigham and Women's Hospital, Harvard Medical School Verified email at mit.edu Phillip Buckhaults The … 19. Abramson et al. Google Scholar Profile. This demonstrates a significant dependence of degree of degradation on the light intensity experienced by the gel, as the light intensity drops from nearly 11.4 mW cm −2 at a distance of 0 mm to 0.9 mW cm −2 at a distance of 30 mm. Corresponding Author: Giovanni Traverso MB, BChir, PhD, Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 3-340, Cambridge, MA 02139 (cgt20@mit.edu). Google Scholar Cross Ref; David Browning and R H. Mellen. Giovanni Traverso Dept. We have developed an Injection Molded Autoclavable, Scalable, Conformable (iMASC) system for aerosol-based protection. This demonstrates a significant dependence of degree of degradation on the light intensity experienced by the gel, as the light intensity drops from nearly 11.4 mW cm −2 at a distance of 0 mm to 0.9 mW cm −2 at a distance of 30 mm. Reducing the frequency at which a patient must take a medication can improve patient adherence. One of the first practical applications of this technology involves the examination of microsatellite markers in sporadic cancers with mismatch-repair deficiencies. Giovanni Traverso. S Babaee, J Shim, JC Weaver, ER Chen, N Patel, K Bertoldi. Engineering precision. of Mechanical Engineering, MIT; Brigham and Women's Hospital, Harvard Medical School Verified email at mit.edu Liangfang Zhang Joan and Irwin Jacobs Chancellor Professor, University of California San Diego Verified email at ucsd.edu Alternative means for drug delivery are needed to facilitate drug adherence and administration. Giovanni Traverso is an Assistant Professor in the Department of Mechanical Engineering at the Massachusetts Institute of Technology (MIT) and also a gastroenterologist in the Division of Gastroenterology, Brigham and Women’s Hospital (BWH), Harvard Medical School. Verified email at mit.edu - Homepage. of Mechanical Engineering, MIT; Brigham and Women's Hospital, Harvard Medical School Verified email at mit.edu Liangfang Zhang Professor of Nanoengineering, University of California - San Diego Verified email at ucsd.edu There is an immediate need for therapies related to coronavirus disease 2019 (COVID-19), especially candidate drugs that possess anti-inflammatory and immunomodulatory effects with low toxicity profiles. Although Mycobacterium tuberculosis (TB) infections are effectively treated with antibiotics, treatment requiring multigram dosing can pose considerable challenges for patients in resource-constrained environments. The following articles are merged in Scholar. meta-analysis mouse behavior aging cognitive training expertise. These preliminary results demonstrate progress that is an easy pill to … ... CAS Article Google Scholar 5. Google Scholar. Science. Giovanni Sala. E-mail: ctraverso@partners.org. SIGCOMM, pages 417--431, Budapest, Hungary, 2018. Oral delivery is the simplest and least invasive way to deliver many pharmaceuticals, but many drugs and medications, including insulin, cannot survive passage through the stomach or the gastrointestinal tract. Many areas of biomedical research depend on the analysis of uncommon variations in individual genes or transcripts. developed an ingestible gastric resident dosage form that releases the contraceptive levonorgestrel. The device successfully measured … Welles AP, Buller MJ, Margolis L, Economos D, Hoyt RW, Richter MW. A long duration of inflammatory bowel disease (IBD) increases the risk for colorectal cancer. There is a dire need for personal protective equipment (PPE) within healthcare settings during the COVID-19 pandemic. Giovanni Traverso is an Instructor of Medicine, Division of Gastroenterology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA. Yunfei Ma, Zhihong Luo, Christoph Steiger, Giovanni Traverso, and Fadel Adib. “ Photometric stereo endoscopy.” Journal of Biomedical Optics 18 (2013): 076017-076017. This "Cited by" count includes citations to the following articles in Scholar. Giovanni Traverso is an Instructor of Medicine, Division of Gastroenterology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA. Robert Langer is an Institute Professor at the Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Enabling Deep-Tissue Networking for Miniature Medical Devices. This allowed a precise millimetric analysis of each inked margin. Natsuda Navamajiti. 403--410. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA. Alpaca: Intermittent execution without checkpoints. Verified email at fujita-hu.ac.jp. The ones marked * may be different from the article in the profile. Res. Although most colorectal cancers are chromosomally unstable, the basis for this instability has not been defined. developed an ingestible delivery vehicle that could self-reorient from any starting position so as to attach to the gastric wall. Biologic drugs — molecular weight, dose, solubility and volume. gi_lab@mailworks.org. Join Facebook to connect with Giovanni Traverso and others you may know. 5. Google Scholar. 0000-0001-7851-4077 Giovanni Traverso 4. Thermal-work strain during Marine rifle squad operations in Afghanistan. Articles Cited by Public access Co-authors. Kirtane et al. Google Scholar; J.L. 1984. Google Scholar; W. C. Brown. developed a drug delivery system that is compatible with nasogastric administration consisting of bead-like drug pills on a shape memory wire … Pottel J, Armstrong D, Zou L, Fekete A, Huang XP, Torosyan H, et al. Giovanni Traverso. In particular, single use disposable N95 face masks have been limited in supply. In Proceedings of the 2018 Conference of the ACM Special Interest Group on Data Communication, pages 417--431, 2018. Google Scholar 4. … Direct-acting antiviral (DAA) therapy is highly effective against hepatitis C virus (HCV). Abstract Cargill, R. et al. Yong Lin Kong & Giovanni Traverso Division of Gastroenterology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, USA Giovanni Traverso Robert Langer is an Institute Professor at the Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Yunfei Ma, Zhihong Luo, Christoph Steiger, Giovanni Traverso, and Fadel Adib. Professor of Finance & Econometrics, Cass Business School, London (U.K.), Professor of Econometrics, Department of Management, Economics and Quantitative Methods, University of Bergamo (Italy) Verified email at city.ac.uk - Homepage. 5. Giovanni Traverso and Robert Langer explain the gastrointestinal frontier. Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Kirtane et al. Some health systems do not have the capacity to accommodate this surge in ventilator demand, leading to shortages and inevitable mortality. Enabling deep-tissue networking for miniature medical devices. StampEd Assembly of polymer Layers-fabricated controlled-release microparticles. Year. pmid:24083930. 0000-0001-7851-4077 Giovanni Traverso 4. IEEE Transactions on Microwave Theory and Techniques 32, 9 (Sep. 1984), 1230--1242. CAS PubMed Google Scholar 23. Rapid detection of translation-terminating mutations at the adenomatous polyposis coli (APC) gene by direct protein truncation test. 3D soft metamaterials with negative Poisson's ratio. Microchips embedding a magnetic sensor and a radiofrequency transmitter can be localized in the body of a mouse at submillimetre resolution when under a magnetic field. Google Scholar. of Mechanical Engineering, MIT; Brigham and Women's Hospital, Harvard Medical School. We have developed a long-acting DAA system (LA-DAAS) that can support multigram … Epub 2013/10/03. Mechanical properties of open-cell rhombic dodecahedron cellular structures. Mil Med. Microneedles (MNs) have been previously investigated transdermally for drug delivery. Giovanni Urga. The generation of long-acting modes of DAA delivery could thus expand HCV treatment. Giovanni Traverso Dept. Google Scholar Digital Library; ... Giovanni Traverso, and Fadel Adib. These preliminary results demonstrate progress that is an easy pill to … View Article PubMed/NCBI Google Scholar 5. developed an ingestible gastric resident dosage form that releases the contraceptive levonorgestrel. Attenuation of Low-Frequency Sound in the Sea: Recent Results. Detection of mutations in faecal DNA represents a promising, non-invasive approach for detecting colorectal cancers in average-risk populations. Merged citations. Chaddock, G. et al. Novel MRI tests of orocecal transit time and whole gut transit time: Studies in normal subjects. We performed whole-exome sequencing analyses to characterize the genetic landscape of these tumors. Dept. 1987. Dept. Parot, Vicente, Daryl Lim, Germán González, Giovanni Traverso, Norman S Nishioka, Benjamin J Vakoc, and Nicholas J Durr. Some self-help groups for individuals with aberrant sexual interests (e.g., Sexaholics Anonymous and Sex and Love Addicts Anonymous) maintain that a period of “sexual sobriety” is necessary for treatment. Bryan Laulicht, Giovanni Traverso, Vikram Deshpande, Robert Langer, and Jeffrey M. Karp. ... Robert Langer and Giovanni Traverso on drug delivery systems. Engineering precision. Advanced Materials 25 (36), 5044-5049. , 2013. Giovanni Traverso, Chetan Bettegowda, Jürgen Kraus, Michael R. Speicher, Kenneth W. Kinzler, Bert Vogelstein and Christoph Lengauer Giovanni Traverso Find this author on Google Scholar The activities of drug inactive ingredients on biological targets. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA. 2017. Giovanni Traverso Dept. 517. 2018. One of the most common side effects of radiation therapy is injury to the gastrointestinal (GI) tract. Google Scholar Cross Ref; Dagdeviren, C. The future of bionic dynamos. Mutation analysis of limited numbers of genes has indicated that colorectal tumors that develop in patients with IBD differ from those of patients without IBD. Google Scholar Cross Ref; Coviello, C., and Sibul, L. Blind source separation and beamforming: algebraic technique analysis. Some clinicians have, of … The COVID-19 pandemic is overwhelming healthcare systems worldwide. Simple battery armor to protect against gastrointestinal injury from accidental ingestion. Giovanni Traverso. CAS Article Google Scholar 22. In In ACM SIGCOMM. Pharm. A phosphopantetheinyl transferase that is essential for mitochondrial fatty acid biosynthesis. To reduce radiation-induced injury, personalized 3D … Despite this, the burden of chronic HCV remains high, particularly in populations for whom daily medications can be challenging. Giovanni Traverso, Carl M. Schoellhammer, and Avi Schroeder contributed equally to this work. Biomedical Engineering Drug Delivery Cancer Genetics. Their combined citations are counted only for the first article. To determine whether genes shown to cause chromosomal instability in model systems were mutated in colorectal cancers, we identified their human homologues and determined their sequence in a panel of colorectal cancers. ... Juri Kiyokawa, Hiroaki Nagashima, Aaron Lopes, Zain A. Tirmizi, Christine K. Lee, Giovanni Traverso, Daniel P. Cahill, Hiroaki Wakimoto . The History of Power Transmission by Radio Waves. X Guan, H Chen, A Abramson, H Man, J Wu, O Yu, BJ Nikolau. Ruby Maa, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts. Articles Cited by Public access Co-authors. Find this author on PubMed. Mimee et al. combined biosensor bacteria with a miniaturized wireless readout capsule to produce a minimally invasive device capable of in vivo biosensing in harsh, difficult-to-access environments (see the Perspective by Gibson and Burgell). 2020 Jul 24;369(6502):403–13. Purpose: Using a standardized specimen protocol analysis, this study aimed to evaluate the resection margin status of patients who underwent resection for either distal cholangiocarcinoma (DC) or pancreatic ductal adenocarcinoma (PDAC). Bacteria are environmentally resilient and can be engineered to sense various biomolecules. ACM. View the profiles of people named Giovanni Traverso. IEEE Transactions on Aerospace and Electronic Systems 40, 1 (2004), 221--235. Google Scholar 45. van der Luijt R, Khan PM, Vasen H, et al. E-mail: rlanger@mit.edu. Particles are fabricated by (a) heating and pressing polymer between a patterned PDMS base mold and a Teflon surface, (b) transferring these bases to a new substrate and filling them with a model drug of interest, then (c) aligning an array of particle caps with drug-filled bases and briefly applying a low … Fujita Health University. Table 1. Cited by. 2013;178(10):1141–8. Search for more papers by this author. E-mail: rlanger@mit.edu. The aggressive primary brain tumor glioblastoma (GBM) is characterized by aberrant metabolism that fuels its malignant phenotype. In Proc. Levonorgestrel was detected in the serum of pigs for 1 month after oral administration of a single dose. 2013. To date, drug loading into MNs has been limited by drug solubility in the polymeric blend. of Mechanical Engineering, MIT; Brigham and Women's Hospital, Harvard Medical School - Цитирано 8.700. пута - Biomedical Engineering - Drug Delivery - Cancer Genetics Here, Verma et al. We hypothesized the application of pleiotropic tetracyclines as potential therapeutic candidates. Google Scholar Cross Ref Econometric Methodology and Applications Panel Data Econometrics Financial Econometrics. Enabling deep-tissue networking for miniature medical devices.
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